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GLP-1 Comparison
Tirzepatide vs Semaglutide — Cost Per mg Breakdown 2026
📅 June 2, 2026
⏱ 6 min read
🔄 Updated daily
Semaglutide and Tirzepatide are the two dominant GLP-1 peptides in the research space. But which one gives you more bang for your buck? We broke down the real cost per mg across all 12 vendors we track — with every discount code already applied.
At a Glance
💉 Semaglutide
$2.49/mg
Best price per mg (Ion Peptide)
💉 Tirzepatide
$4.90/mg
Best price per mg (Ion Peptide)
Semaglutide is significantly cheaper per mg across every vendor we track. Tirzepatide commands a premium, typically 1.5–2× the cost of Semaglutide at the same vendor.
Semaglutide Prices — All Vendors (June 2026)
| Vendor | Price | Size | Cost/mg |
|---|
| Ion Peptide Cheapest | $24.90 | 10mg | $2.49/mg |
| Puratek Peptides | $24.95 | 5mg | $4.99/mg |
| EZ Peptides | $27.00 | 10mg | $2.70/mg |
| Glacier Aminos | $29.99 | 15mg | $2.00/mg |
| Ascension Peptides | $65.00 | 5mg | $13.00/mg |
| MileHigh Compounds | $49.99 | 10mg | $5.00/mg |
| Nura Peptide | $45.00 | 10mg | $4.50/mg |
| RetaOne Labs | $29.00 | 10mg | $2.90/mg |
Tirzepatide Prices — All Vendors (June 2026)
| Vendor | Price | Size | Cost/mg |
|---|
| Ion Peptide Cheapest | $49.00 | 10mg | $4.90/mg |
| Puratek Peptides | $39.95 | 10mg | $3.99/mg |
| EZ Peptides | $53.00 | 10mg | $5.30/mg |
| Glacier Aminos | $68.99 | 10mg | $6.90/mg |
| MileHigh Compounds | $89.99 | 10mg | $9.00/mg |
| Nura Peptide | $69.00 | 10mg | $6.90/mg |
| Labsourced | $109.00 | 30mg | $3.63/mg |
| RetaOne Labs | $24.00 | 10mg | $2.40/mg |
💡 Key Insight: Semaglutide is cheaper per mg at almost every vendor. If budget is a primary concern, Semaglutide offers more value. Tirzepatide's premium reflects its dual GIP/GLP-1 mechanism, which is why it commands higher prices in research markets.
Compare Live GLP-1 Prices
Prices update daily. See both side by side on the live tracker.
Compare Now →
Semaglutide vs Tirzepatide — Key Differences
Mechanism
Semaglutide is a GLP-1 receptor agonist — it mimics glucagon-like peptide 1. Tirzepatide is a dual GIP/GLP-1 receptor agonist, acting on both glucose-dependent insulinotropic polypeptide and GLP-1 receptors simultaneously. This dual action is why Tirzepatide is generally considered the more potent compound in clinical research.
Price
Semaglutide is consistently cheaper across all vendors — typically by 30–50% per mg. For budget-conscious research, Semaglutide offers more milligrams per dollar.
Availability
Both are widely available across all 12 vendors we track. Semaglutide occasionally sees stock shortages due to demand. Use our tracker to find who has inventory right now.
Which Should You Research?
This is entirely dependent on your research goals. Both peptides are extensively studied. Tirzepatide's dual mechanism makes it a more novel target for research, while Semaglutide has a longer published research history. On price alone, Semaglutide wins every time.
Frequently Asked Questions
Is Tirzepatide more expensive than Semaglutide?
Yes — Tirzepatide is typically 1.5–2× more expensive per mg than Semaglutide across all vendors we track. The premium reflects its newer, dual-action mechanism.
Which vendor has the cheapest Tirzepatide?
RetaOne Labs currently offers the lowest entry price for Tirzepatide at $24/10mg. Check our
live Tirzepatide tracker for today's current data.
Which vendor has the cheapest Semaglutide?
Ion Peptide consistently offers the lowest cost per mg for Semaglutide. See the
live Semaglutide tracker for today's prices.
Are research peptide GLP-1s legal?
Research peptides are sold legally for laboratory purposes only. They are not approved for human consumption. Always check your local regulations before purchasing.
⚠️ Disclaimer: PepsTracker is a price comparison tool only. All products listed are for research purposes only and are not intended for human consumption. We do not manufacture, sell, or endorse any products or vendors. Prices are updated daily but may not reflect real-time changes.