Synthetic tetrapeptide from the pineal gland that activates telomerase and may extend cellular lifespan.
Activates telomerase enzyme, which extends telomeres and delays cellular senescence. Also regulates melatonin production, antioxidant activity, and normalizes circadian rhythms through pineal gland modulation.
Developed by the St. Petersburg Institute of Bioregulation and Gerontology. Original research was conducted by Dr. Vladimir Khavinson over several decades. Often cycled 2–3 times per year in research protocols.
The telomerase activation mechanism is particularly notable — telomere shortening is considered a primary driver of cellular aging, and Epithalon's ability to extend telomeres in cell culture and animal studies has generated significant longevity research interest.