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Glutathione

Skin / Antioxidant

The body's master antioxidant — a tripeptide essential for detoxification, immune function, and skin brightening.

Half-life
~7 minutes (IV) / hours (SubQ)
Research dose
600–1500mg IV/SubQ
Frequency
Weekly to 3× weekly
Routes
IV, SubQ, or oral (liposomal)

How it works

A tripeptide (γ-Glu-Cys-Gly) produced in all cells, but most abundantly in the liver. Neutralises reactive oxygen species (ROS) via its thiol group, conjugates toxins for excretion (Phase II detoxification), recycles vitamins C and E, and inhibits tyrosinase enzyme — shifting melanin synthesis from eumelanin to phaeomelanin, producing skin-lightening effects.

Research uses

Antioxidant research
Skin brightening
Detoxification support
Immune function
Oxidative stress reduction

Research notes

Glutathione depletion is associated with virtually every major chronic disease and age-related condition. IV and SubQ administration bypasses the poor oral bioavailability of standard glutathione (liposomal forms have better oral bioavailability).

The skin-brightening effect is well-documented in clinical studies, resulting from competitive inhibition of tyrosinase (the rate-limiting enzyme in melanin synthesis). This application drives significant commercial and research interest in Asia.

Storage

❄️Freeze lyophilized powder
🌡️Refrigerate once reconstituted — use promptly
📅Use within 24–48 hours of reconstitution

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