NAD+ (nicotinamide adenine dinucleotide) is a coenzyme central to cellular energy and redox reactions; levels decline with age. It's studied for mitochondrial and metabolic function and is generally compatible as an adjunct to other stacks (see the stacking guide). Often sold in large 500–1000 mg vials.
Epithalon (Epitalon) is a synthetic tetrapeptide studied in the context of telomerase activity and circadian/longevity research.
MOTS-c is a mitochondrial-derived peptide studied for metabolic regulation and exercise-mimetic effects.
SS-31 targets the inner mitochondrial membrane (cardiolipin) and is studied for mitochondrial function and cellular energy.
| Compound | Focus |
|---|---|
| NAD+ | Energy / redox coenzyme |
| Epithalon | Telomerase / circadian |
| MOTS-c | Mitochondrial / metabolic |
| SS-31 | Mitochondrial membrane |
These target different aspects of cellular aging, so they're often discussed as a complementary longevity cluster rather than substitutes.
PepsTracker tracks all four across 26 vendors on cost-per-mg — important here because NAD+ vials are large. Platinum Peptides carries them, 15% off with pepstracker15. Search any compound on the homepage.
The most-studied longevity research compounds include NAD+ (energy/redox coenzyme), Epithalon (telomerase/circadian), MOTS-c (mitochondrial/metabolic) and SS-31 (mitochondrial membrane). They are sold for research use only.
NAD+ acts on cellular energy and redox pathways and is generally compatible as an adjunct to other stacks, though it is used adjunctively rather than for direct synergy.
Compare on cost-per-milligram — especially for NAD+, which is sold in large 500 to 1000 mg vials. PepsTracker normalizes prices across 26 vendors with discount codes applied.