A pineal-derived tripeptide from the Khavinson series, studied for cognitive protection and circadian regulation.
A tripeptide (Glu-Asp-Arg) bioregulator targeting pineal gland tissue. Research from the St. Petersburg Institute of Bioregulation suggests it penetrates the blood-brain barrier, interacts with DNA regulatory regions in neurons, and normalises expression of genes involved in circadian rhythm, neuroprotection, and antioxidant defence.
Part of the Khavinson tetrapeptide and dipeptide bioregulator series, which claims tissue-specific effects by interacting with promoter regions of target genes. The scientific literature is predominantly from Russian institutions.
Used in clinical settings in Russia for age-related memory decline and neurodegenerative prevention. Typically administered in 10-day courses repeated 2–4 times per year in bioregulator protocols.