A combined nootropic stack targeting cognitive enhancement and anxiety relief simultaneously.
Combines Semax (ACTH 4-7 analogue — activates BDNF/TrkB signalling, upregulates NGF, enhances dopaminergic and serotonergic tone) with Selank (tuftsin analogue — modulates GABAergic tone for anxiolysis, normalises serotonin metabolism, immunomodulatory). The combination addresses both cognitive performance and anxiety/stress simultaneously through complementary mechanisms.
The combination is particularly useful in research contexts where anxiety and cognitive impairment co-occur — Selank reduces the anxiety that impairs Semax's cognitive benefits, while Semax provides the cognitive uplift that Selank alone does not.
Commonly used as a nasal spray combination. Both peptides are approved or available in Russia as nasal drops, and the combination is well-established in Russian nootropic medicine.