A pegylated IGF-1 splice variant that activates muscle satellite cells for repair and growth.
Mechano Growth Factor (MGF) is a splice variant of IGF-1 produced locally in damaged muscle tissue. PEGylation extends its half-life from minutes to ~24 hours. It binds a unique receptor site to activate quiescent satellite cells, which then fuse with damaged muscle fibres to enable repair and hypertrophy.
Unlike systemic IGF-1, MGF acts locally at the site of muscle damage. The PEG modification allows it to circulate long enough to reach muscle tissue systemically, making injectable administration relevant.
Often stacked with IGF-1 LR3: PEG-MGF is administered post-workout to activate satellite cells, followed by IGF-1 LR3 to drive proliferation of those activated cells.